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Setting The Record Straight: Erectile DysfunctionThis is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Storage of Viagra?Metabolism and Excretion: Sildenafil is cleared predominantly by the CYP3A4 (major route) and CYP2C9 (minor route) hepatic microsomal isoenzymes. The major circulating metabolite results from N-desmethylation of sildenafil, and is itself further metabolized. This metabolite has a PDE selectivity profile similar to sildenafil and an in vitro potency for PDE5 approximately 50% of the parent drug. Plasma concentrations of this metabolite are approximately 40% of those seen for sildenafil, so that the metabolite accounts for about 20% of sildenafil's pharmacologic effects. viagra for woman The recommended dose of CIALIS for once daily use is 5 mg, taken at approximately the same time every day, without regard to timing of sexual activity.about cialis and cialis types Start a discussion The reason behind this advice is actually pretty obvious – Tadalafil, which is the main active ingredient in Cialis, works by lowering blood pressure. Alcohol is known to produce the same effect, so, when consumed in really large amounts along with Tadalafil, it can make your blood pressure drop to really low levels causing dizziness, lightheadedness, nausea, headache, and, of course, inability to get or maintain a healthy erection.

Viagra (sildenafil) works by inhibiting the chemical phosphodiesterase, which leads to an increase in the effect of nitric oxide. Nitric oxide allows the smooth muscles inside the penis to relax, promoting more blood flow to the area during sexual arousal or stimulation. Nitric oxide also opens the blood vessels throughout the body, which can cause decreased blood pressure. This decrease in blood pressure may increase the effects of blood-pressure lowering drugs, especially alpha-blockers, such as terazosin (Hytrin), doxazosin (Cardura), and prazosin (Minipress). Patients with cardiovascular disease could have additional side effects from Viagra, especially in combination with sexual activity. Other common side effects of Viagra include warmth or redness in your face, neck, or chest; stuffy nose; headache; upset stomach; and back pain. More serious, but less frequent side effects include prolonged erection lasting more than 4 hours, vision changes, and loss of hearing. If these occur, you should contact your health care provider. buy cialis online without prescription

In addition to the above, there are other minor symptoms also: cialis results Ever since the FDA's April approval of Viagra, the little blue pill giving insurance companies a headache, the media have been infatuated with male impotence and its potential cure. U.S. pharmacists dispensed more than 215,000 Viagra prescriptions within the first four weeks of availability, sending manufacturer Pfizer Inc.'s stocks soaring and journalists buzzing. Everyone from porn magazine editors to former presidential hopefuls have expounded upon the supposed sociocultural impact of a wonderdrug clinically proven to, shall we say, make man's best friend stand up and salute the flag.2.5 mg Cialis tabletOphthalmologic — blurred vision, changes in color vision, conjunctivitis (including conjunctival hyperemia), eye pain, lacrimation increase, swelling of eyelids

For oral erectile dysfunction medicines to work as desired, they must be used properly in the first place. This means taking the medicine 30–45 minutes before engaging in sexual intimacy; taking the drug on an empty stomach or at least avoiding a heavy or high-fat meal before taking the drug (this is especially important when using sildenafil); and engaging in adequate genital stimulation before attempting intercourse. Drinking small amounts of alcohol (one to two drinks) should not compromise the effectiveness of erectile dysfunction medicines, but larger amounts of alcohol can diminish a man’s ability to have an erection.

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